University of Hawaii at Hilo Catalog 2013–2014

Ph.D. in Pharmaceutical Sciences

Home » Graduate Education » Daniel K. Inouye College of Pharmacy (CoP) Graduate Programs » Ph.D. in Pharmaceutical Sciences

Program Director: Edward Fisher, Ph.D., RPh (fishere@hawaii.edu)
Ph.D. Program Director
College of Pharmacy
722 A'ohoku St.
Hilo, HI 96720
Tel: (808) 932-7698

University of Hawaiʻi at Hilo, College of Pharmacy (UH Hilo CoP)
Office of Student Services (OSS)
Ph.D. Program Admissions
200 W. Kāwili Street
Hilo, HI 96720
Fax: (808) 932-7138
Email: pharmacy@hawaii.edu


Faculty:

  • Julie Ann Luiz Adrian, D.V.M. Assistant Professor
  • André S. Bachmann, Ph.D. Chair and Associate Professor
  • Forrest Batz, Pharm.D. Assistant Professor
  • Robert P. Borris, Ph.D. Associate Dean for Research and Associate Professor
  • Leng Chee Chang, Ph.D. Assistant Professor
  • Mahavir Chougule, Ph.D. Assistant Professor
  • Linda Connelly, Ph.D. Assistant Professor
  • Edward Fisher, Ph.D. Associate Dean for Academic Affairs and Professor
  • Daniela Gündisch, Ph.D. Assistant Professor
  • Aaron Jacobs, Ph.D. Assistant Professor
  • Susan Jarvi, Ph.D. Director, Pre-Pharmacy Program and Associate Professor
  • Tamara P. Kondratyuk, Ph.D. Laboratory Manager and Assistant Specialist
  • Dana-Lynn Koomoa-Lange, Ph.D., Assistant Professor
  • Russell J. Molyneux, Ph.D. Affiliate Faculty
  • Kenneth R. Morris, Ph.D. Professor
  • Anthony Otsuka, Ph.D. Instructor
  • John M. Pezzuto, Ph.D. Dean and Professor
  • Dianqing Sun, Ph.D. Assistant Professor
  • Ghee T. Tan, Ph.D. Assistant Professor
  • Gary R. Ten Eyck, Ph.D. Assistant Professor
  • Supakit Wongwiwatthananukit, Pharm.D., Ph.D. Assistant Professor
  • Anthony D. Wright, Ph.D. Associate Professor

Program Description

Utilizing the extraordinary intellectual, biological, physical and cultural diversity of its geographic region as a focus of investigation and study, the University of Hawaiʻi at Hilo’s College of Pharmacy is proud to offer a Ph.D. program in the Pharmaceutical Sciences.

This program, which is the only program of its type in the Pacific region, provides graduate training in the Pharmaceutical Sciences including; Medicinal Chemistry, Pharmacology, Pharmaceutics, and Pharmacognosy. It is aimed at students with B.S., M.S., or Pharm.D. degrees, and those currently working in the field. Studies culminate with the award of a Ph.D. in Pharmaceutical Sciences, with an emphasis on natural products discovery and development and their importance in pharmacy and healthcare.

Students will be prepared for senior leadership positions in the pharmaceutical sciences in academia, research, education, government, industry and related fields and become leaders who can identify, research, and problem solve issues related to the pharmaceutical sciences. The Ph.D. program is designed to foster student development as critical thinkers, team players, self-directed interdisciplinary scholars and communicators.

Mission

The mission of the Ph.D. program in Pharmaceutical Sciences is to train students to be skilled researchers and critical thinkers who will play key leadership roles in furthering the development of the Pharmaceutical Sciences and related fields now and into the future.

Student Learning Outcomes

At the conclusion of the PhD program a graduate should be able to:

  1. Perform scientific research that will advance knowledge in the interdisciplinary field of Pharmaceutical Sciences.
  2. Use advanced technological equipment in order to perform quantitative analysis and be able to interpret complex data.
  3. Analyze, apply, and present research findings. 
  4. Prepare, interpret, and critique scientific publications and proposals.
  5. Identify which aspects of their individual program may be usefully transferred to some applied research program.
  6. Complete the seven stages for a successful PhD in any technical discipline, thereby  becoming an independent researcher:
  • Identify a problem/question
  • Form an hypothesis
  • Develop a model
  • Design an experimental strategy to test the hypothesis
  • Execute an experimental plan
  • Interpret the data against the hypothesis
  • Report the results in a dissertation and peer reviewed publications

Admission Requirements

Acceptance is granted at the discretion of the Pharmaceutical Science Ph.D. Admissions Committee based on the criteria below.

  1. Successful completion of the Ph.D. in Pharmaceutical Sciences Application process.
  2. Applicants must have a B.S., M.S., Pharm.D. and/or equivalent degree.
  3. Applicants must have a minimum Grade Point Average of 3.0 out of 4.0 or the equivalent in the last 60 semester credits of undergraduate and in all post-baccalaureate work.
  4. Applicants must have successfully completed with a grade “C” or higher: General Biology I and II for Science Majors with Labs, General Chemistry I and II for Science Majors with Labs, Organic Chemistry I and II for Science Majors with Labs, Calculus 1 or Advanced Calculus.
  5. A personal statement of objectives is required which includes applicant's background, professional goals and academic and research interests.
  6. Resume.
  7. Official Graduate Record Examination (GRE) scores sent directly from ETS: minimum 153 verbal, 144 quantitative, and 4.5 for analytical.
  8. Three Letters of Recommendation using the “Ph.D. Letter of Recommendation Form”. The letters should be written by people who can speak to the applicant's educational ability, motivation, and character, and/or leadership experiences. At least one of your letters MUST be written by a Professor of one of the Natural or Physical Sciences. Please allow the Recommenders plenty of time to complete this form, and have them mail the letter directly to the UH Hilo-CoP, Ph.D. Program Admission Office.
  9. Completed SKYPE or equivalent electronic interview

Foreign applicants must also submit:

  1. Official TOEFL score report.
  2. International Graduate Student SupplementalInformation Form hilo.hawaii.edu/admissions/forms/documents/sup-form.pdf.

Further information on the details of fulfilling admissions requirements are available from the Ph.D. Program Admissions Office pharmacy@hawaii.edu, and at pharmacy.uhh.hawaii.edu/academics/graduate/admissions.php.

Graduation Requirements

  1. Successful achievement of candidate status after year one of the student’s program.
  2. Regardless of any previous graduate experience, a minimum of 24 graduate didactic credit hours must be taken at UH Hilo before the Ph.D. degree can be granted.
  3. Completion of all first year graduate courses with no grades lower than a “B” and all subsequent courses with an average grade of no less than "B".
  4. Completion of one seminar each year; a minimum grade of “B” should be achieved for this presentation.
  5. No later than the third year of the program successful completion of a comprehensive oral examination following a seminar presentation of the candidate’s plans for their dissertation. In this examination the student’s Graduate Committee will determine if the student is sufficiently prepared in the selected field of study to continue with their dissertation.
  6. Successful completion of a dissertation, with enrollment in a minimum of 56 credits of PHPS 800. Upon completion of the dissertation a final oral dissertation defense will follow.
  7. Completion of at least 96 combined credits of graduate courses and dissertation; PHPS 600, PHPS 700 and PHPS 800.
  8. Compliance with UH Hilo rules and regulations for graduation.

Curricula

To successfully complete the PhD degree candidates must complete; qualifying year 1 (Minimum GPA = 3.0), a minimum of 24 graduate level didactic credits; after first year courses must be completed with GPA average of no less than 3.0; a minimum 56 credits of Dissertation; a minimum of 96 credit hours overall (Minimum average GPA = 3.0).

PhD Year 1 (Qualifying Year) Fall Courses Total of 11 credits

  • PHPS 750 PhD Overview of the Pharmaceutical Sciences (3)
  • PHPS 751 PhD Biochemistry I–Biomolecules (4)
  • PHPS 755 Advanced Pharmaceutics I, including Dosage Form Design and Processing (3)
  • PHPS 718 Research Laboratory Rotation and Graduate Seminar (1)

PhD Year 1 (Qualifying Year) Spring Courses Total of 13 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (6)
  • PHPS 752 PhD Biochemistry I–Biomolecules (4)
  • PHPS 756 Advanced Pharmaceutics II, including Dosage Form Design and Processing (3)

PhD Year 1 Summer Courses Total minimum of 6 credits

  • PHPS 800 Dissertation Research (Minimum 6)

PhD Year 2 Fall Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 2 Spring Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 2 Summer Courses Total minimum of 6 credits

  • PHPS 800 Dissertation Research (Minimum 6)

PhD Year 3 Fall Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 3 Spring Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 3 Summer Courses Total minimum of 6 credits

  • PHPS 800 Dissertation Research (Minimum 6)

PhD Year 4 Fall Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 4 Spring Courses Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

PhD Year 4 Summer Courses Total minimum of 6 credits

  • PHPS 800 Dissertation Research (Minimum 6)

PhD Year 5 and beyond are taken on an as required basis. Total minimum of 12 credits

  • PHPS 800 Dissertation Research and Graduate Seminar (Minimum 6)
  • Electives (No minimum)

Electives–Listed Alphabetically

Alpha/Number Course Title Credits
PHPS 701 Apoptosis and Angiogenesis in Disease Processes and Drug Development 1
PHPS 702 Biological Evaluation of Natural Products 3
PHPS 703 Cancer Biology 2
PHPS 704 Combinatorial Chemistry and High Throughput Technologies in Drug Discovery 2
PHPS 705 Designing Clinical Research 3
PHPS 706 Environmental Toxicology 2
PHPS 707 Genetics in Medicine 2
PHPS 708 Isolation methods for natural product discovery 2
PHPS 709 Instrumental methods and structure elucidation of mainly natural products 2
PHPS 710 Laboratory Animal Care, Management and Medicine I 2
PHPS 711 Laboratory Animal Care, Management and Medicine II 2
PHPS 712 Medical Cell Biology 2
PHPS 713 Medicinal Chemistry I 2
PHPS 714 Medicinal Chemistry II 2
PHPS 715 Medicinal Chemistry III 2
PHPS 716 Medicinal Chemistry IV 2
PHPS 717 Medicinal Chemistry of CNS Drugs and Development of in vivo CNS Tracers 2
PHPS 719 Molecular Biology Techniques and Applications for Healthcare Professionals 2
PHPS 720 Natural Products and Cancer Chemoprevention 2
PHPS 721 Neuropsychopharmacology 2
PHPS 722 Pharmaceutical Marketing 2
PHPS 723 Pharmacognosy 2
PHPS 724 Pharmacology I 3
PHPS 725 Pharmacology II 3
PHPS 726 Pharmacology III 3
PHPS 727 Pharmacology IV 3
PHPS 728 Phytochemistry of Terrestrial Plants 2
PHPS 729 Receptor Theory and Signal Transduction 2
PHPS 730 Sample collection, documentation and preservation 1
PHPS 731 Toxicants and Toxicity 3
PHPS 732 Toxic plant natural products and their therapeutic potential 2

Rev. 9/3/13